宋玉君




宋玉君
教授
Email: ysong@nju.edu.cn


研究方向
微流控芯片,生物分析化学,生物纳米材料,转化医学

个人简介
2005年毕业于武汉大学化学系获学士学位,2011年1月毕业于中国科学院长春应用化学研究所获博士学位,之后在康奈尔大学医学院附属卫理公会医院从事博士后研究。2015年入选中组部第十一批青年千人计划。迄今已发表学术论文20多篇,包括一作的Nat. Commun,Angew Chem,JACS , Adv Mater 和Nucleic Acid Res等,并受邀在Trends in Biotechbology 上撰写综述性文章,所有文章共被引用一千六百多次,部分研究工作被Nature网站头条、Nature China、RSC Chemistry World, ScienceDaily、Phys.org、Chicago Tribune,科技时报等近百家媒体网站Highlight或报道。申请国际发明专利一项,并成功转让给美国加州的一家生物医学诊断公司。

科研成果
文章:

Li, Y.; Xuan, J.; Song, Y.; Qi, W.; He, B.; Wang, P.; Qin, L.*, Nanoporous Glass Integrated in Volumetric Bar-Chart Chip for Point-of-Care Diagnostics of Non-Small Cell Lung Cancer. Acs Nano2016,10 (1), 1640-1647.

Wang, Y.; Li, Y.; Qi, W.; Song, Y.*, Luminescent lanthanide graphene for detection of bacterial spores and cysteine. Chemical Communications2015,51 (55), 11022-11025.

Li, Y.; Xuan, J.; Song, Y.; Wang, P.; Qin, L.*, A microfluidic platform with digital readout and ultra-low detection limit for quantitative point-of-care diagnostics. Lab on a Chip2015,15 (16), 3300-3306.

Li, Y.; Xuan, J.; Xia, T.; Han, X.; Song, Y.; Cao, Z.; Jiang, X.; Guo, Y.; Wang, P.; Qin, L.*, Competitive Volumetric Bar-Chart Chip with Real-Time Internal Control for Point-of-Care Diagnostics. Analytical Chemistry 2015,87 (7), 3771-3777.

Song, Y.; Xia, X.; Wu, X.; Wang, P.; Qin, L.*, Integration of Platinum Nanoparticles with a Volumetric Bar-Chart Chip for Biomarker Assays. Angewandte Chemie-International Edition2014,53 (46), 12451-12455.

Song, Y.; Huang, Y.-Y.; Liu, X.; Zhang, X.; Ferrari, M.; Qin, L.*, Point-of-care technologies for molecular diagnostics using a drop of blood. Trends in Biotechnology2014,32 (3), 132-139.

Song, Y.; Wang, Y.; Qin, L.*, A Multistage Volumetric Bar Chart Chip for Visualized Quantification of DNA.Journal of the American Chemical Society 2013,135 (45), 16785-16788.

Song, Y.; Zhang, Y.; Bernard, P. E.; Reuben, J. M.; Ueno, N. T.; Arlinghaus, R. B.; Zu, Y.; Qin, L.*, Multiplexed volumetric bar-chart chip for point-of-care diagnostics. Nature Communications2012,3. 1283

Song, Y.; Wei, W.; Qu, X.*, Colorimetric Biosensing Using Smart Materials. Advanced Materials 2011,23 (37), 4215-4236.

Song, Y.; Xu, C.; Wei, W.; Ren, J.; Qu, X.*, Light regulation of peroxidase activity by spiropyran functionalized carbon nanotubes used for label-free colorimetric detection of lysozyme. Chemical Communications 2011,47 (32), 9083-9085.

Song, Y.; Chen, Y.; Feng, L.; Ren, J.; Qu, X.*, Selective and quantitative cancer cell detection using target-directed functionalized graphene and its synergetic peroxidase-like activity. Chemical Communications 2011,47 (15), 4436-4438.

Song, Y.; Feng, L.; Ren, J.; Qu, X.*, Stabilization of unstable CGC(+) triplex DNA by single-walled carbon nanotubes under physiological conditions. Nucleic Acids Research2011,39 (15), 6835-6843.

Zhao, C.; Qu, K.; Song, Y.; Ren, J.; Qu, X.*, A Universal, Label-Free, and Sensitive Optical Enzyme-Sensing System for Nuclease and Methyltransferase Activity Based on Light Scattering of Carbon Nanotubes. Advanced Functional Materials2011,21 (3), 583-590.

Song, Y.; Qu, K.; Xu, C.; Ren, J.; Qu, X.*, Visual and quantitative detection of copper ions using magnetic silica nanoparticles clicked on multiwalled carbon nanotubes. Chemical Communications2010,46 (35), 6572-6574.

Song, Y.; Qu, K.; Zhao, C.; Ren, J.; Qu, X.*, Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection. Advanced Materials2010,22 (19), 2206-+.

Song, Y.; Wang, X.; Zhao, C.; Qu, K.; Ren, J.; Qu, X.*, Label-Free Colorimetric Detection of Single Nucleotide Polymorphism by Using Single-Walled Carbon Nanotube Intrinsic Peroxidase-Like Activity. Chemistry-a European Journal2010,16 (12), 3617-3621.

Wang, X.; Wang, C.; Qu, K.; Song, Y.; Ren, J.; Miyoshi, D.; Sugimoto, N.; Qu, X.*, Ultrasensitive and Selective Detection of a Prognostic Indicator in Early-Stage Cancer Using Graphene Oxide and Carbon Nanotubes. Advanced Functional Materials2010,20 (22), 3967-3971.

Zhao, C.; Qu, K.; Song, Y.; Xu, C.; Ren, J.; Qu, X.*, A Reusable DNA Single-Walled Carbon-Nanotube-Based Fluorescent Sensor for Highly Sensitive and Selective Detection of Ag+ and Cysteine in Aqueous Solutions. Chemistry-a European Journal2010,16 (27), 8147-8154.

Zhao, C.; Song, Y.; Qu, K.; Ren, J.; Qu, X.*, Luminescent Rare-Earth Complex Covalently Modified Single-Walled Carbon Nanotubes: Design, Synthesis, and DNA Sequence-Dependent Red Luminescence Enhancement. Chemistry of Materials2010,22 (20), 5718-5724.

Song, Y.; Zhao, C.; Ren, J.; Qu, X.*, Rapid and ultra-sensitive detection of AMP using a fluorescent and magnetic nano-silica sandwich complex. Chemical Communications2009, (15), 1975-1977.

Wang, X.; Song, Y.; Ren, J.; Qu, X.*, Knocking-Down Cyclin A(2) by siRNA Suppresses Apoptosis and Switches Differentiation Pathways in K562 Cells upon Administration with Doxorubicin. Plos One2009,4 (8).

Zhao, C.; Song, Y.; Ren, J.; Qu, X.*, A DNA nanomachine induced by single-walled carbon nanotubes on gold surface. Biomaterials2009,30 (9), 1739-1745.

Peng, Y.; Song, Y.; Feng, L.; Ren, J.; Qu, X.*, 7-Amino actinomycin D bound to single-stranded hairpin DNA enhanced by loop sequence-dependent luminescent Eu3+ and Tb3+ binding. Journal of Inorganic Biochemistry2009,103 (12), 1675-1679.

Zhao, C.; Peng, Y.; Song, Y.; Ren, J.; Qu, X.*, Self-assembly of single-stranded RNA on carbon nanotube: Polyadenylic acid to form a duplex structure. Small2008,4 (5), 656-661.

专利:

Qin, L.;Song, Y., Multiplexed volumetric bar chart chip for point of care biomarker and/or analyte quantitation,USA,PCT/US2013/065270。

其他:
招收和培养研究生情况以及学生获得的荣誉:
每年招收1-2名博士研究生,2-3名硕士研究生。
欢迎博士后、专职科研队伍及访问学者加盟!
如有兴趣,请联系:ysong@nju.edu.cn