王学堃



王学堃

助理研究员


Email: Xuekunwang0610@126.com


研究方向:
小分子药物的设计、合成与生物活性研究
个人简介:
20156月博士毕业于中国药科大学,博士期间从事新型降血糖药物的开发。20157月至今南京大学现代工程与应用科学学院助理研究员,主要从事功能性小分子化合物的设计与合成。
科研成果
文章:

1.Xuekun Wang, Tianxiao Zhao, Baowei Yang. Synthesis and biological evaluation of Phenoxyacetic acid Derivatives as Novel Free Fatty Acid Receptor 1 Agonists [J]. Bioorganic & Medicinal Chemistry, 2014, 23 (1) 132–140.

2.Xuekun Wang, Ying Li, Baowei Yang C-Aryl Glucosides with Substituents at the Distal Aryl Ring as Sodium-Dependent Glucose Cotransporter Inhibitors for the Treatment of Diabetes Mellitus[J] Chemical Biology & Drug Design, 2015, 86 (2) 246–253.

3.Zheng Li, Xuekun Wang, Xue Xu  Design, synthesis and structure–activity relationship studies of novel phenoxyacetamide-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes[J] Chemical Biology & Drug Design, 2015, 23 (20) 6666–6672.

4.Zheng Li, Xuekun Wang, Xue Xu Design, synthesis and biological activity of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists [J] Chemical Biology & Drug Design, 2015 , 23 (22)7158–7164.

5.王学堃,钱海,黄文龙,治疗糖尿病的新策略—SGLT2抑制剂,《药物化学进展》第十卷

6.黄文龙;钱海;王学堃 C-芳基葡萄糖苷SGLT2抑制剂,专利申请号:201410030395.X

7.黄文龙;钱海;王学堃 苯氧乙酸类衍生物、其制备方法及其作为药物的用途专利申请号:201410548763.X