报告题目：Chelator Free Radiolabeled Nanomaterials for Positron Emission Tomography Imaging
报告摘要：Nanomaterials (NMs) have attracted much attention as probes for tumor imaging due to their unique physical properties as well as the ease of surface functionalization. Radionuclide imaging has an important role in cancer diagnosis due to its unique advantages like high sensitivity and the ability to conduct quantitative analysis of whole-body images. We have developed many radiolabeled nanoplatforms. For example, we directly doped 64Cu into quantum dots (QDs) via cation exchange reaction. These self-illuminated 64Cu doped QDs show greatly enhanced Cerenkov resonance energy transfer efficiency and have been successfully applied for in vivo luminescence and PET (positron emission tomography) imaging. We also integrated 64Cu onto polyethylene glycol stabilized Au NMs via chemical reduction. Our 64Cu integrated NMs are proved to be radiochemically stable and can provide the accurate distribution of Au NMs via non-invasive PET imaging. These intrinsically radioactive NMs are emerging probes for theranostic applications. They also provide a rigid way to monitor the in vivo fate of nanoparticles.