李喆




李喆
教授
办公室地址:蒙民伟楼1401室
办公室电话:025-83592983
Email: zheli@nju.edu.cn


实验室主页:http://lilab.nju.edu.cn

研究方向

DNA nanotechnology
开设课程
Molecular Biology
个人简介:
李喆教授本科毕业于北京大学生命科学学院,博士毕业于亚利桑那州立大学化学与生物化学系,入职前于耶鲁大学从事博士后研究。2015年入选中组部第十一批“青年千人计划”。主要研究方向包括DNA纳米结构在生物体内的自组装、DNA折纸结构的高阶折叠,以及高效率改造微生物基因。在国际知名刊物发表论文十余篇,迄今为止引用近300次,担任多个国际知名学术杂志审稿人。
科研成果
文章:

1.Alexis Rovner, Adrian Haimovich, Spencer Katz, Zhe Li, Michael Grome, Brandon Gassaway, Miriam Amiram, Ryan Gallagher, Jesse Rinehart, Jaymin Patel and Farren Isaacs, Recoded organisms engineered to require synthetic amino acids for viability, Nature 518, 89-93 (2015)

2.Ryan R Gallagher*, Zhe Li*, Aaron O Lewis and Farren J Isaacs, Rapid editing and evolution of bacterial genomes using libraries of synthetic DNA, Nature Protocols 9, 2301-2316 (2014)

3.Zhe Li, Lei Wang, Hao Yan and Yan Liu, Effect of DNA hairpin loops on the twist of planar DNA origami tiles, Langmuir 28, 1959-1965 (2012)

4.Zhe Li, Minghui Liu, Lei Wang, Jeanette Nangreave, Hao Yan and Yan Liu, Molecular behavior of DNA origami in higher order self-assembly, J. Am. Chem. Soc. 138, 13545-13552 (2010)

5.Zhe Li, Bryan Wei, Jeanette Nangreave, Chenxiang Lin, Yan Liu, Yongli Mi and Hao Yan, A replicable tetrahedral nanostructure self-assembled from a single DNA strand, J. Am. Chem. Soc. 131, 13093-13098 (2009)

6.Zhe Li, Yonggang Ke, Chenxiang Lin, Hao Yan and Yan Liu, Subtractive assembly of DNA nanoarchitectures driven by fuel strand displacement, Chem. Commun. 4318-4320 (2008)

7.Nicholas Stephanopoulos, Minghui Liu, Gary J. Tong, Zhe Li, Yan Liu, Hao Yan and Matthew B. Francis, Immobilization and one-dimensional arrangement of virus capsids with nanoscale precision using DNA origami, Nano Letters 10, 2714-2720 (2010)

8.Chenxiang Lin, Yonggang Ke, Zhe Li, James H. Wang, Yan Liu and Hao Yan, Mirror image DNA nanostructures for chiral supramolecular assemblies, Nano Letters 9, 433-436 (2009)

9.Chenxiang Lin, Jeanette Nangreave, Zhe Li, Hao Yan and Yan Liu, Signal amplification on a DNA tile based biosensor with enhanced sensitivity, Nanomedicine 3, 521-528 (2008)

10.Nan Zhong, Shengnan Zhang, Peng Zou, Jiaxuan Chen, Xue Kang, Zhe Li, Chao Liang, Changwen Jin and Bin Xia, Without its N-finger, the main protease of severe acute respiratory syndrome coronavirus can form a novel dimer through its C-terminal domain, J. Virol. 82, 4227-4234 (2008).

 

其他
招收和培养研究生情况以及学生获得的荣誉:
每年招收1-2名博士研究生,2-3名硕士研究生。
欢迎博士后及访问学者加盟!如有兴趣,请联系zheli@nju.edu.cn